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In Progress
Clinical

- Study Type: Vaccine

Purpose

Systems biology approach to examine effects of seasonal flu vaccination in adults of different ages on gene expression, cytokine stimulation and serum cytokines with parameters such as immune senescence to uncover new markers and mechanisms behind failure of immune function in many older people.

Hypothesis

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Experimental Design

Total RNA was extracted from whole-blood lysates obtained from individuals immediately prior to vaccination against seasonal influenza, followed by depletion of globin messenger RNA. The goal was to evaluate potential gene expression signatures at Day 0 associated with immune senescence.

Experimental Variables

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Controls

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Methods

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Additional Information

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Microarray
Illumina HumanHT-12 v4
75 Samples Loaded: 75
Human (Homo sapiens)
Whole Blood
Influenza vaccine
Sample Set Spreadsheet
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Samples Preview
Sample ID !Sample Title group time race vaccine
GSM1422001 Baseline (day 0) 5920666012_A Fluzone single-dose syringe White Baseline- D0
GSM1422002 Baseline (day 0) 5920711008_D Fluzone single-dose syringe White Baseline- D0
GSM1422003 Baseline (day 0) 5920834001_J Fluzone multi-dose vial White Baseline- D0
GSM1422004 Baseline (day 0) 5920711008_H Fluzone single-dose syringe White Baseline- D0
GSM1422005 Baseline (day 0) 5920666014_D Fluzone single-dose syringe White Baseline- D0
Please log in in order to upload files.
File
sampleset4000034_sampleannotations_Group.csv
Sample Set Spreadsheet
sampleset4000034_sampleannotations_Group.csv
Sample Set Spreadsheet
Raw Signal
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Links

Samples Viewer / Editor

All fields are editable except the "Sample ID" column. To edit a cell, click within the cell. To edit a "date" cell, click on the calendar icon. To cancel an edit, press the ESC key.

Sample ID !Sample Title Group Time Race Vaccine Sex
GSM1422001
Baseline (day 0) 5920666012_A
Fluzone single-dose syringe
 
White
Baseline- D0
female
GSM1422002
Baseline (day 0) 5920711008_D
Fluzone single-dose syringe
 
White
Baseline- D0
female
GSM1422003
Baseline (day 0) 5920834001_J
Fluzone multi-dose vial
 
White
Baseline- D0
female
GSM1422004
Baseline (day 0) 5920711008_H
Fluzone single-dose syringe
 
White
Baseline- D0
male
GSM1422005
Baseline (day 0) 5920666014_D
Fluzone single-dose syringe
 
White
Baseline- D0
female
GSM1422006
Baseline (day 0) 5920711008_G
Fluzone single-dose syringe
 
White
Baseline- D0
male
GSM1422007
Baseline (day 0) 5920666011_G
Fluzone single-dose syringe
 
White
Baseline- D0
female
GSM1422008
Baseline (day 0) 5920834001_I
Fluzone single-dose syringe
 
White
Baseline- D0
male
GSM1422009
Baseline (day 0) 5920666013_I
Fluzone single-dose syringe
 
White
Baseline- D0
male
GSM1422010
Baseline (day 0) 5920666012_B
Fluzone single-dose syringe
 
White
Baseline- D0
female
GSM1422011
Baseline (day 0) 5920834001_D
Fluzone single-dose syringe
 
White
Baseline- D0
female
GSM1422012
Baseline (day 0) 5920666013_L
Fluzone single-dose syringe
 
White
Baseline- D0
female
GSM1422013
Baseline (day 0) 5920834001_F
Fluzone single-dose syringe
 
White
Baseline- D0
male
GSM1422014
Baseline (day 0) 5920834001_A
Fluzone single-dose syringe
 
White
Baseline- D0
male
GSM1422015
Baseline (day 0) 5920666012_K
Fluzone single-dose syringe
 
White
Baseline- D0
male
GSM1422016
Baseline (day 0) 5920666014_J
Fluzone multi-dose vial
 
White
Baseline- D0
female
GSM1422017
Baseline (day 0) 5920666013_C
Fluzone single-dose syringe
 
Asian
Baseline- D0
male
GSM1422018
Baseline (day 0) 5920666013_G
Fluzone single-dose syringe
 
White
Baseline- D0
female
GSM1422019
Baseline (day 0) 5920666011_I
Fluzone single-dose syringe
 
White
Baseline- D0
female
GSM1422020
Baseline (day 0) 5920666014_H
Fluzone single-dose syringe
 
White
Baseline- D0
female
GSM1422021
Baseline (day 0) 5920666012_D
Fluzone single-dose syringe
 
White
Baseline- D0
female
GSM1422022
Baseline (day 0) 5920666013_F
Fluzone single-dose syringe
 
White
Baseline- D0
female
GSM1422023
Baseline (day 0) 5920711019_C
Fluzone single-dose syringe
 
Asian
Baseline- D0
female
GSM1422024
Baseline (day 0) 5920666014_B
Fluzone single-dose syringe
 
White
Baseline- D0
female
GSM1422025
Baseline (day 0) 5920711008_L
Fluzone single-dose syringe
 
White
Baseline- D0
male
GSM1422026
Baseline (day 0) 5920834001_H
Fluzone single-dose syringe
 
White
Baseline- D0
male
GSM1422027
Baseline (day 0) 5920711008_K
Fluzone single-dose syringe
 
White
Baseline- D0
female
GSM1422028
Baseline (day 0) 5920711019_F
Fluzone single-dose syringe
 
White
Baseline- D0
male
GSM1422029
Baseline (day 0) 5920666012_J
Fluzone single-dose syringe
 
White
Baseline- D0
male
GSM1422030
Baseline (day 0) 5920711019_G
Fluzone single-dose syringe
 
White
Baseline- D0
female
GSM1422031
Baseline (day 0) 5920711008_E
Fluzone single-dose syringe
 
White
Baseline- D0
male
GSM1422032
Baseline (day 0) 5920666011_H
Fluzone single-dose syringe
 
White
Baseline- D0
male
GSM1422033
Baseline (day 0) 5920711019_B
Fluzone single-dose syringe
 
White
Baseline- D0
female
GSM1422034
Baseline (day 0) 5920666014_I
Fluzone single-dose syringe
 
Other
Baseline- D0
female
GSM1422035
Baseline (day 0) 5920711019_K
Fluzone single-dose syringe
 
White
Baseline- D0
male
GSM1422036
Baseline (day 0) 5920711008_A
Fluzone single-dose syringe
 
White
Baseline- D0
female
GSM1422037
Baseline (day 0) 5920666013_K
Fluzone single-dose syringe
 
White
Baseline- D0
female
GSM1422038
Baseline (day 0) 5920711019_E
Fluzone single-dose syringe
 
Asian
Baseline- D0
female
GSM1422039
Baseline (day 0) 5920711008_C
Fluzone single-dose syringe
 
Other
Baseline- D0
female
GSM1422040
Baseline (day 0) 5920834001_B
Fluzone single-dose syringe
 
White
Baseline- D0
female
GSM1422041
Baseline (day 0) 5920666012_H
Fluzone single-dose syringe
 
White
Baseline- D0
male
GSM1422042
Baseline (day 0) 5920711008_J
Fluzone single-dose syringe
 
White
Baseline- D0
male
GSM1422043
Baseline (day 0) 5920666012_L
Fluzone single-dose syringe
 
White
Baseline- D0
female
GSM1422044
Baseline (day 0) 5920666013_A
Fluzone single-dose syringe
 
White
Baseline- D0
female
GSM1422045
Baseline (day 0) 5920666014_E
Fluzone single-dose syringe
 
White
Baseline- D0
female
GSM1422046
Baseline (day 0) 5920834001_E
Fluzone single-dose syringe
 
White
Baseline- D0
male
GSM1422047
Baseline (day 0) 5920666014_A
Fluzone single-dose syringe
 
White
Baseline- D0
male
GSM1422048
Baseline (day 0) 5920711019_J
Fluzone single-dose syringe
 
Other
Baseline- D0
male
GSM1422049
Baseline (day 0) 5920666014_L
Fluzone single-dose syringe
 
Asian
Baseline- D0
female
GSM1422050
Baseline (day 0) 5920666011_K
Fluzone single-dose syringe
 
Asian
Baseline- D0
female
GSM1422051
Baseline (day 0) 5920666014_F
Fluzone single-dose syringe
 
White
Baseline- D0
female
GSM1422052
Baseline (day 0) 5920711019_H
Fluzone single-dose syringe
 
White
Baseline- D0
male
GSM1422053
Baseline (day 0) 5920711019_L
Fluzone single-dose syringe
 
White
Baseline- D0
male
GSM1422054
Baseline (day 0) 5920666013_J
Fluzone single-dose syringe
 
White
Baseline- D0
female
GSM1422055
Baseline (day 0) 5920666012_G
Fluzone single-dose syringe
 
White
Baseline- D0
female
GSM1422056
Baseline (day 0) 5920711019_D
Fluzone single-dose syringe
 
White
Baseline- D0
female
GSM1422057
Baseline (day 0) 5920666013_H
Fluzone single-dose syringe
 
White
Baseline- D0
male
GSM1422058
Baseline (day 0) 5920666012_C
Fluzone single-dose syringe
 
White
Baseline- D0
female
GSM1422059
Baseline (day 0) 5920666013_E
Fluzone single-dose syringe
 
White
Baseline- D0
male
GSM1422060
Baseline (day 0) 5920666011_L
Fluzone single-dose syringe
 
White
Baseline- D0
male
GSM1422061
Baseline (day 0) 5920666014_C
Fluzone single-dose syringe
 
White
Baseline- D0
female
GSM1422062
Baseline (day 0) 5920711008_I
Fluzone single-dose syringe
 
White
Baseline- D0
female
GSM1422063
Baseline (day 0) 5920834001_G
Fluzone single-dose syringe
 
White
Baseline- D0
male
GSM1422064
Baseline (day 0) 5920666012_I
Fluzone single-dose syringe
 
White
Baseline- D0
male
GSM1422065
Baseline (day 0) 5920711019_A
Fluzone single-dose syringe
 
White
Baseline- D0
female
GSM1422066
Baseline (day 0) 5920834001_C
Fluzone single-dose syringe
 
White
Baseline- D0
female
GSM1422067
Baseline (day 0) 5920666013_B
Fluzone single-dose syringe
 
White
Baseline- D0
female
GSM1422068
Baseline (day 0) 5920711008_B
Fluzone single-dose syringe
 
White
Baseline- D0
male
GSM1422069
Baseline (day 0) 5920666014_K
Fluzone single-dose syringe
 
Other
Baseline- D0
female
GSM1422070
Baseline (day 0) 5920666011_J
Fluzone single-dose syringe
 
White
Baseline- D0
male
GSM1422071
Baseline (day 0) 5920666012_E
Fluzone single-dose syringe
 
Asian
Baseline- D0
male
GSM1422072
Baseline (day 0) 5920711019_I
Fluzone single-dose syringe
 
White
Baseline- D0
female
GSM1422073
Baseline (day 0) 5920666014_G
Fluzone single-dose syringe
 
White
Baseline- D0
female
GSM1422074
Baseline (day 0) 5920666012_F
Fluzone single-dose syringe
 
White
Baseline- D0
male
GSM1422075
Baseline (day 0) 5920711008_F
Fluzone single-dose syringe
 
White
Baseline- D0
male

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