Sample Set Annotation Tool: Time Course of Young Adults Vaccinated with Influenza TIV Vaccine during 2008/09 Flu Season. GSE29617

Study Design
Assay
Sample Info
Files
Info
Samples
Group Sets
Analysis

Purpose

Systems vaccinology has emerged as an interdisciplinary field that combines systems wide measurements and network and predictive modeling applied to vaccinology.Here we used the systems vaccinology approach to study the molecular mechanisms underlying the innate responses to the trivalent inactivated influenza (TIV) and live attenuated influenza (LAIV) vaccination in humans, and to identify early gene signatures that predict the magnitude of the antibody responses to influenza vaccination.

Hypothesis

Experimental Design

During the 2008 influenza season, healthy adults were vaccinated with TIV (28 vaccinees), and blood samples isolated at days 0, 3, 7 post-vaccination. Microarrays were performed using total RNA extracted from the peripheral blood mononuclear cells of vaccinees.

Experimental Variables

Controls

Methods

Additional Information

Expected Samples:

80 Samples Loaded: 80

Species

Human (Homo sapiens)

Sample Source

PBMC

Disease

Influenza vaccine

Treatment Protocol

Growth Protocol

Extraction Protocol

Storage Conditions

Sample Set Spreadsheet

Please log in in order to upload files.

Samples Preview

Sample ID	!Sample Title	group	Cell type	vaccine	Subject id
GSM733942	2008 TIV subject ID 2 at D0 post-vaccination	Day0 post vaccination	PBMC	TIV (Fluarix, GlaxoSmithKline Biologicals)	2
GSM733943	2008 TIV subject ID 2 at D7 post-vaccination	Day7 post vaccination	PBMC	TIV (Fluarix, GlaxoSmithKline Biologicals)	2
GSM733944	2008 TIV subject ID 16 at D0 post-vaccination	Day0 post vaccination	PBMC	TIV (Fluarix, GlaxoSmithKline Biologicals)	16
GSM733945	2008 TIV subject ID 16 at D3 post-vaccination	Day3 post vaccination	PBMC	TIV (Fluarix, GlaxoSmithKline Biologicals)	16
GSM733946	2008 TIV subject ID 16 at D7 post-vaccination	Day7 post vaccination	PBMC	TIV (Fluarix, GlaxoSmithKline Biologicals)	16

Please log in in order to upload files.

File
sampleset4000069_sampleannotations_Group.csv Sample Set Spreadsheet
sampleset4000069_sampleannotations_Group.csv Sample Set Spreadsheet

Samples Viewer / Editor

All fields are editable except the "Sample ID" column. To edit a cell, click within the cell. To edit a "date" cell, click on the calendar icon. To cancel an edit, press the ESC key.

Sample ID	!Sample Title	Group	Cell type	Vaccine	Subject id	Time point	Hai titer (day 0) - a/brisbane/59/2007 (h1n1)	Hai titer (day 0) - a/uruguay (h3n2)	Hai titer (day 0) - b/brisbane/3/2007	Hai titer (day 28) - a/brisbane/59/2007 (h1n1)	Hai titer (day 28) - a/uruguay (h3n2)	Hai titer (day 28) - b/brisbane/3/2007
GSM733942	2008 TIV subject ID 2 at D0 post-vaccination	Day0 post vaccination	PBMC	TIV (Fluarix, GlaxoSmithKline Biologicals)	2	D0	5	5	5	160	80	40
GSM733943	2008 TIV subject ID 2 at D7 post-vaccination	Day7 post vaccination	PBMC	TIV (Fluarix, GlaxoSmithKline Biologicals)	2	D7	5	5	5	160	80	40
GSM733944	2008 TIV subject ID 16 at D0 post-vaccination	Day0 post vaccination	PBMC	TIV (Fluarix, GlaxoSmithKline Biologicals)	16	D0	20	5	5	20	5	5
GSM733945	2008 TIV subject ID 16 at D3 post-vaccination	Day3 post vaccination	PBMC	TIV (Fluarix, GlaxoSmithKline Biologicals)	16	D3	20	5	5	20	5	5
GSM733946	2008 TIV subject ID 16 at D7 post-vaccination	Day7 post vaccination	PBMC	TIV (Fluarix, GlaxoSmithKline Biologicals)	16	D7	20	5	5	20	5	5
GSM733947	2008 TIV subject ID 29 at D0 post-vaccination	Day0 post vaccination	PBMC	TIV (Fluarix, GlaxoSmithKline Biologicals)	29	D0	10	5	20	640	640	80
GSM733948	2008 TIV subject ID 29 at D3 post-vaccination	Day3 post vaccination	PBMC	TIV (Fluarix, GlaxoSmithKline Biologicals)	29	D3	10	5	20	640	640	80
GSM733949	2008 TIV subject ID 29 at D7 post-vaccination	Day7 post vaccination	PBMC	TIV (Fluarix, GlaxoSmithKline Biologicals)	29	D7	10	5	20	640	640	80
GSM733950	2008 TIV subject ID 3 at D0 post-vaccination	Day0 post vaccination	PBMC	TIV (Fluarix, GlaxoSmithKline Biologicals)	3	D0	160	5	80	160	80	80
GSM733951	2008 TIV subject ID 3 at D3 post-vaccination	Day3 post vaccination	PBMC	TIV (Fluarix, GlaxoSmithKline Biologicals)	3	D3	160	5	80	160	80	80
GSM733952	2008 TIV subject ID 3 at D7 post-vaccination	Day7 post vaccination	PBMC	TIV (Fluarix, GlaxoSmithKline Biologicals)	3	D7	160	5	80	160	80	80
GSM733953	2008 TIV subject ID 32 at D0 post-vaccination	Day0 post vaccination	PBMC	TIV (Fluarix, GlaxoSmithKline Biologicals)	32	D0	320	40	160	320	160	160
GSM733954	2008 TIV subject ID 32 at D3 post-vaccination	Day3 post vaccination	PBMC	TIV (Fluarix, GlaxoSmithKline Biologicals)	32	D3	320	40	160	320	160	160
GSM733955	2008 TIV subject ID 32 at D7 post-vaccination	Day7 post vaccination	PBMC	TIV (Fluarix, GlaxoSmithKline Biologicals)	32	D7	320	40	160	320	160	160
GSM733956	2008 TIV subject ID 35 at D0 post-vaccination	Day0 post vaccination	PBMC	TIV (Fluarix, GlaxoSmithKline Biologicals)	35	D0	5	5	5	20	5	5
GSM733957	2008 TIV subject ID 35 at D3 post-vaccination	Day3 post vaccination	PBMC	TIV (Fluarix, GlaxoSmithKline Biologicals)	35	D3	5	5	5	20	5	5
GSM733958	2008 TIV subject ID 35 at D7 post-vaccination	Day7 post vaccination	PBMC	TIV (Fluarix, GlaxoSmithKline Biologicals)	35	D7	5	5	5	20	5	5
GSM733959	2008 TIV subject ID 38 at D0 post-vaccination	Day0 post vaccination	PBMC	TIV (Fluarix, GlaxoSmithKline Biologicals)	38	D0	20	5	5	20	5	5
GSM733960	2008 TIV subject ID 38 at D3 post-vaccination	Day3 post vaccination	PBMC	TIV (Fluarix, GlaxoSmithKline Biologicals)	38	D3	20	5	5	20	5	5
GSM733961	2008 TIV subject ID 38 at D7 post-vaccination	Day7 post vaccination	PBMC	TIV (Fluarix, GlaxoSmithKline Biologicals)	38	D7	20	5	5	20	5	5
GSM733962	2008 TIV subject ID 39 at D0 post-vaccination	Day0 post vaccination	PBMC	TIV (Fluarix, GlaxoSmithKline Biologicals)	39	D0	320	80	320	320	320	320
GSM733963	2008 TIV subject ID 39 at D3 post-vaccination	Day3 post vaccination	PBMC	TIV (Fluarix, GlaxoSmithKline Biologicals)	39	D3	320	80	320	320	320	320
GSM733964	2008 TIV subject ID 39 at D7 post-vaccination	Day7 post vaccination	PBMC	TIV (Fluarix, GlaxoSmithKline Biologicals)	39	D7	320	80	320	320	320	320
GSM733965	2008 TIV subject ID 4 at D0 post-vaccination	Day0 post vaccination	PBMC	TIV (Fluarix, GlaxoSmithKline Biologicals)	4	D0	640	5	80	640	80	160
GSM733966	2008 TIV subject ID 4 at D3 post-vaccination	Day3 post vaccination	PBMC	TIV (Fluarix, GlaxoSmithKline Biologicals)	4	D3	640	5	80	640	80	160
GSM733967	2008 TIV subject ID 42 at D0 post-vaccination	Day0 post vaccination	PBMC	TIV (Fluarix, GlaxoSmithKline Biologicals)	42	D0	5	5	5	5	5	5
GSM733968	2008 TIV subject ID 42 at D3 post-vaccination	Day3 post vaccination	PBMC	TIV (Fluarix, GlaxoSmithKline Biologicals)	42	D3	5	5	5	5	5	5
GSM733969	2008 TIV subject ID 42 at D7 post-vaccination	Day7 post vaccination	PBMC	TIV (Fluarix, GlaxoSmithKline Biologicals)	42	D7	5	5	5	5	5	5
GSM733970	2008 TIV subject ID 43 at D0 post-vaccination	Day0 post vaccination	PBMC	TIV (Fluarix, GlaxoSmithKline Biologicals)	43	D0	10	5	40	320	320	160
GSM733971	2008 TIV subject ID 43 at D3 post-vaccination	Day3 post vaccination	PBMC	TIV (Fluarix, GlaxoSmithKline Biologicals)	43	D3	10	5	40	320	320	160
GSM733972	2008 TIV subject ID 43 at D7 post-vaccination	Day7 post vaccination	PBMC	TIV (Fluarix, GlaxoSmithKline Biologicals)	43	D7	10	5	40	320	320	160
GSM733973	2008 TIV subject ID 44 at D0 post-vaccination	Day0 post vaccination	PBMC	TIV (Fluarix, GlaxoSmithKline Biologicals)	44	D0	160	20	5	160	320	160
GSM733974	2008 TIV subject ID 44 at D3 post-vaccination	Day3 post vaccination	PBMC	TIV (Fluarix, GlaxoSmithKline Biologicals)	44	D3	160	20	5	160	320	160
GSM733975	2008 TIV subject ID 44 at D7 post-vaccination	Day7 post vaccination	PBMC	TIV (Fluarix, GlaxoSmithKline Biologicals)	44	D7	160	20	5	160	320	160
GSM733976	2008 TIV subject ID 46 at D0 post-vaccination	Day0 post vaccination	PBMC	TIV (Fluarix, GlaxoSmithKline Biologicals)	46	D0	40	320	80	80	640	80
GSM733977	2008 TIV subject ID 46 at D3 post-vaccination	Day3 post vaccination	PBMC	TIV (Fluarix, GlaxoSmithKline Biologicals)	46	D3	40	320	80	80	640	80
GSM733978	2008 TIV subject ID 46 at D7 post-vaccination	Day7 post vaccination	PBMC	TIV (Fluarix, GlaxoSmithKline Biologicals)	46	D7	40	320	80	80	640	80
GSM733979	2008 TIV subject ID 47 at D0 post-vaccination	Day0 post vaccination	PBMC	TIV (Fluarix, GlaxoSmithKline Biologicals)	47	D0	160	640	40	160	640	40
GSM733980	2008 TIV subject ID 47 at D3 post-vaccination	Day3 post vaccination	PBMC	TIV (Fluarix, GlaxoSmithKline Biologicals)	47	D3	160	640	40	160	640	40
GSM733981	2008 TIV subject ID 47 at D7 post-vaccination	Day7 post vaccination	PBMC	TIV (Fluarix, GlaxoSmithKline Biologicals)	47	D7	160	640	40	160	640	40
GSM733982	2008 TIV subject ID 48 at D0 post-vaccination	Day0 post vaccination	PBMC	TIV (Fluarix, GlaxoSmithKline Biologicals)	48	D0	640	5	20	160	80	160
GSM733983	2008 TIV subject ID 48 at D3 post-vaccination	Day3 post vaccination	PBMC	TIV (Fluarix, GlaxoSmithKline Biologicals)	48	D3	640	5	20	160	80	160
GSM733984	2008 TIV subject ID 48 at D7 post-vaccination	Day7 post vaccination	PBMC	TIV (Fluarix, GlaxoSmithKline Biologicals)	48	D7	640	5	20	160	80	160
GSM733985	2008 TIV subject ID 51 at D0 post-vaccination	Day0 post vaccination	PBMC	TIV (Fluarix, GlaxoSmithKline Biologicals)	51	D0	80	5	40	160	320	80
GSM733986	2008 TIV subject ID 51 at D3 post-vaccination	Day3 post vaccination	PBMC	TIV (Fluarix, GlaxoSmithKline Biologicals)	51	D3	80	5	40	160	320	80
GSM733987	2008 TIV subject ID 53 at D0 post-vaccination	Day0 post vaccination	PBMC	TIV (Fluarix, GlaxoSmithKline Biologicals)	53	D0	40	5	20	40	40	160
GSM733988	2008 TIV subject ID 53 at D3 post-vaccination	Day3 post vaccination	PBMC	TIV (Fluarix, GlaxoSmithKline Biologicals)	53	D3	40	5	20	40	40	160
GSM733989	2008 TIV subject ID 53 at D7 post-vaccination	Day7 post vaccination	PBMC	TIV (Fluarix, GlaxoSmithKline Biologicals)	53	D7	40	5	20	40	40	160
GSM733990	2008 TIV subject ID 63 at D0 post-vaccination	Day0 post vaccination	PBMC	TIV (Fluarix, GlaxoSmithKline Biologicals)	63	D0	5	5	5	40	40	5
GSM733991	2008 TIV subject ID 63 at D3 post-vaccination	Day3 post vaccination	PBMC	TIV (Fluarix, GlaxoSmithKline Biologicals)	63	D3	5	5	5	40	40	5
GSM733992	2008 TIV subject ID 63 at D7 post-vaccination	Day7 post vaccination	PBMC	TIV (Fluarix, GlaxoSmithKline Biologicals)	63	D7	5	5	5	40	40	5
GSM733993	2008 TIV subject ID 65 at D0 post-vaccination	Day0 post vaccination	PBMC	TIV (Fluarix, GlaxoSmithKline Biologicals)	65	D0	5	20	20	40	40	20
GSM733994	2008 TIV subject ID 65 at D3 post-vaccination	Day3 post vaccination	PBMC	TIV (Fluarix, GlaxoSmithKline Biologicals)	65	D3	5	20	20	40	40	20
GSM733995	2008 TIV subject ID 65 at D7 post-vaccination	Day7 post vaccination	PBMC	TIV (Fluarix, GlaxoSmithKline Biologicals)	65	D7	5	20	20	40	40	20
GSM733996	2008 TIV subject ID 68 at D0 post-vaccination	Day0 post vaccination	PBMC	TIV (Fluarix, GlaxoSmithKline Biologicals)	68	D0	5	5	5	320	5	5
GSM733997	2008 TIV subject ID 68 at D3 post-vaccination	Day3 post vaccination	PBMC	TIV (Fluarix, GlaxoSmithKline Biologicals)	68	D3	5	5	5	320	5	5
GSM733998	2008 TIV subject ID 68 at D7 post-vaccination	Day7 post vaccination	PBMC	TIV (Fluarix, GlaxoSmithKline Biologicals)	68	D7	5	5	5	320	5	5
GSM733999	2008 TIV subject ID 70 at D0 post-vaccination	Day0 post vaccination	PBMC	TIV (Fluarix, GlaxoSmithKline Biologicals)	70	D0	5	5	5	80	5	5
GSM734000	2008 TIV subject ID 70 at D7 post-vaccination	Day7 post vaccination	PBMC	TIV (Fluarix, GlaxoSmithKline Biologicals)	70	D7	5	5	5	80	5	5
GSM734001	2008 TIV subject ID 72 at D0 post-vaccination	Day0 post vaccination	PBMC	TIV (Fluarix, GlaxoSmithKline Biologicals)	72	D0	5	5	5	40	40	5
GSM734002	2008 TIV subject ID 72 at D3 post-vaccination	Day3 post vaccination	PBMC	TIV (Fluarix, GlaxoSmithKline Biologicals)	72	D3	5	5	5	40	40	5
GSM734003	2008 TIV subject ID 72 at D7 post-vaccination	Day7 post vaccination	PBMC	TIV (Fluarix, GlaxoSmithKline Biologicals)	72	D7	5	5	5	40	40	5
GSM734004	2008 TIV subject ID 73 at D0 post-vaccination	Day0 post vaccination	PBMC	TIV (Fluarix, GlaxoSmithKline Biologicals)	73	D0	5	5	5	80	160	80
GSM734005	2008 TIV subject ID 73 at D3 post-vaccination	Day3 post vaccination	PBMC	TIV (Fluarix, GlaxoSmithKline Biologicals)	73	D3	5	5	5	80	160	80
GSM734006	2008 TIV subject ID 73 at D7 post-vaccination	Day7 post vaccination	PBMC	TIV (Fluarix, GlaxoSmithKline Biologicals)	73	D7	5	5	5	80	160	80
GSM734007	2008 TIV subject ID 74 at D0 post-vaccination	Day0 post vaccination	PBMC	TIV (Fluarix, GlaxoSmithKline Biologicals)	74	D0	5	5	5	40	160	5
GSM734008	2008 TIV subject ID 74 at D3 post-vaccination	Day3 post vaccination	PBMC	TIV (Fluarix, GlaxoSmithKline Biologicals)	74	D3	5	5	5	40	160	5
GSM734009	2008 TIV subject ID 74 at D7 post-vaccination	Day7 post vaccination	PBMC	TIV (Fluarix, GlaxoSmithKline Biologicals)	74	D7	5	5	5	40	160	5
GSM734010	2008 TIV subject ID 78 at D0 post-vaccination	Day0 post vaccination	PBMC	TIV (Fluarix, GlaxoSmithKline Biologicals)	78	D0	20	5	5	20	80	5
GSM734011	2008 TIV subject ID 78 at D3 post-vaccination	Day3 post vaccination	PBMC	TIV (Fluarix, GlaxoSmithKline Biologicals)	78	D3	20	5	5	20	80	5
GSM734012	2008 TIV subject ID 78 at D7 post-vaccination	Day7 post vaccination	PBMC	TIV (Fluarix, GlaxoSmithKline Biologicals)	78	D7	20	5	5	20	80	5
GSM734013	2008 TIV subject ID 80 at D0 post-vaccination	Day0 post vaccination	PBMC	TIV (Fluarix, GlaxoSmithKline Biologicals)	80	D0	80	5	20	80	5	20
GSM734014	2008 TIV subject ID 80 at D3 post-vaccination	Day3 post vaccination	PBMC	TIV (Fluarix, GlaxoSmithKline Biologicals)	80	D3	80	5	20	80	5	20
GSM734015	2008 TIV subject ID 80 at D7 post-vaccination	Day7 post vaccination	PBMC	TIV (Fluarix, GlaxoSmithKline Biologicals)	80	D7	80	5	20	80	5	20
GSM734016	2008 TIV subject ID 83 at D0 post-vaccination	Day0 post vaccination	PBMC	TIV (Fluarix, GlaxoSmithKline Biologicals)	83	D0	5	5	10	80	5	80
GSM734017	2008 TIV subject ID 83 at D3 post-vaccination	Day3 post vaccination	PBMC	TIV (Fluarix, GlaxoSmithKline Biologicals)	83	D3	5	5	10	80	5	80
GSM734018	2008 TIV subject ID 83 at D7 post-vaccination	Day7 post vaccination	PBMC	TIV (Fluarix, GlaxoSmithKline Biologicals)	83	D7	5	5	10	80	5	80
GSM734019	2008 TIV subject ID 85 at D0 post-vaccination	Day0 post vaccination	PBMC	TIV (Fluarix, GlaxoSmithKline Biologicals)	85	D0	80	5	320	80	40	40
GSM734020	2008 TIV subject ID 85 at D3 post-vaccination	Day3 post vaccination	PBMC	TIV (Fluarix, GlaxoSmithKline Biologicals)	85	D3	80	5	320	80	40	40
GSM734021	2008 TIV subject ID 85 at D7 post-vaccination	Day7 post vaccination	PBMC	TIV (Fluarix, GlaxoSmithKline Biologicals)	85	D7	80	5	320	80	40	40

Group Sets View in Gene Expression Browser

Name
All Samples	Default	View
In order to make new Group Sets or change settings, please log in.

Module Analysis

Group Set
All Samples

SIDRA