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In Progress
Clinical

- Study Type: Natural Infection

Purpose

Diagnosis of severe influenza pneumonia remains challenging because of the lack of correlation between presence of influenza virus and patient’s clinical status. We conducted gene expression profiling in the whole blood of critically ill patients to identify a gene signature that would allow clinicians to distinguish influenza infection from other causes of severe respiratory failure (e.g. bacterial pneumonia, non-infective systemic inflammatory response syndrome). Methods: Whole blood samples were collected from critically ill individuals and assayed on Illumina HT-12 gene expression beadarrays. Differentially expressed genes were determined by linear mixed model analysis and over-represented biological pathways determined using GeneGo MetaCore. Results: The gene expression profile of H1N1 influenza A pneumonia was distinctly different from bacterial pneumonia and systemic inflammatory response syndrome. The influenza gene expression profile is characterized by up-regulation of genes from cell cycle regulation, apoptosis and DNA-damage response pathways. In contrast, no distinctive gene-expression signature was found in patients with bacterial pneumonia or systemic inflammatory response syndrome. The gene expression profile of influenza infection persisted through five days of follow-up. Furthermore, in patients with primary H1N1 influenza A infection who subsequently developed bacterial co-infection, the influenza gene-expression signature remained unaltered, despite the presence of a super-imposed bacterial infection. Conclusions: The whole blood expression profiling data indicates that the host response to influenza pneumonia is distinctly different from that caused by bacterial pathogens. This information may speed up identification of the cause of infection in patients presenting with severe respiratory failure, allowing appropriate patient care to be undertaken more rapidly.

Hypothesis

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Experimental Design

Daily PAXgene samples for up to 5 days for; influenza A pneumonia patients (n=8), bacterial pneumonia patients (n=16), mixed bacterial and influenza A pneumonia patients (n=3), systemic inflammatory response patients (SIRS, n=13). Days 1 and 5 PAXgene samples for healthy control individuals

Experimental Variables

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Controls

--

Methods

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Additional Information

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Microarray
Illumina HumanHT-12 v3
190 Samples Loaded: 190
Human (Homo sapiens)
Whole Blood
Influenza, Pneumonia
Sample Set Spreadsheet
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Samples Preview
Sample ID !Sample Title Gender tissue group day
GSM983403 PAXgene whole blood, SIRS,Day_3,ID=23 male PAXgene whole blood SIRS day3 3
GSM983404 PAXgene whole blood, SIRS,Day_2,ID=23 male PAXgene whole blood SIRS day2 2
GSM983405 PAXgene whole blood, SIRS,Day_1,ID=23 male PAXgene whole blood SIRS day1 1
GSM983406 PAXgene whole blood, Bacteria pneumonia,Day_3,ID=1 female PAXgene whole blood Bacteria day3 3
GSM983407 PAXgene whole blood, Bacteria pneumonia,Day_1,ID=33 female PAXgene whole blood Bacteria day1 1
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File
sampleset4000026_sampleannotations_Group.csv
Sample Set Spreadsheet
sampleset4000026_sampleannotations_Group.csv
Sample Set Spreadsheet
Raw Signal
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Links

Samples Viewer / Editor

All fields are editable except the "Sample ID" column. To edit a cell, click within the cell. To edit a "date" cell, click on the calendar icon. To cancel an edit, press the ESC key.

Sample ID !Sample Title Gender Tissue Group Day ID Sample type
GSM983403
PAXgene whole blood, SIRS,Day_3,ID=23
male
PAXgene whole blood
SIRS day3
3
23
systemic inflammatory response
GSM983404
PAXgene whole blood, SIRS,Day_2,ID=23
male
PAXgene whole blood
SIRS day2
2
23
systemic inflammatory response
GSM983405
PAXgene whole blood, SIRS,Day_1,ID=23
male
PAXgene whole blood
SIRS day1
1
23
systemic inflammatory response
GSM983406
PAXgene whole blood, Bacteria pneumonia,Day_3,ID=1
female
PAXgene whole blood
Bacteria day3
3
1
Bacteria pneumonia
GSM983407
PAXgene whole blood, Bacteria pneumonia,Day_1,ID=33
female
PAXgene whole blood
Bacteria day1
1
33
Bacteria pneumonia
GSM983408
PAXgene whole blood, Bacteria pneumonia,Day_2,ID=33
female
PAXgene whole blood
Bacteria day2
2
33
Bacteria pneumonia
GSM983409
PAXgene whole blood, Bacteria pneumonia,Day_3,ID=33
female
PAXgene whole blood
Bacteria day3
3
33
Bacteria pneumonia
GSM983410
PAXgene whole blood, SIRS,Day_3,ID=4
male
PAXgene whole blood
SIRS day3
3
4
systemic inflammatory response
GSM983411
PAXgene whole blood, Bacteria pneumonia,Day_4,ID=1
female
PAXgene whole blood
Bacteria day4
4
1
Bacteria pneumonia
GSM983412
PAXgene whole blood, SIRS,Day_4,ID=23
male
PAXgene whole blood
SIRS day4
4
23
systemic inflammatory response
GSM983413
PAXgene whole blood, SIRS,Day_5,ID=23
male
PAXgene whole blood
SIRS day5
5
23
systemic inflammatory response
GSM983414
PAXgene whole blood, Bacteria pneumonia,Day_5,ID=1
female
PAXgene whole blood
Bacteria day5
5
1
Bacteria pneumonia
GSM983415
PAXgene whole blood, SIRS,Day_2,ID=4
male
PAXgene whole blood
SIRS day2
2
4
systemic inflammatory response
GSM983416
PAXgene whole blood, Bacteria pneumonia,Day_1,ID=1
female
PAXgene whole blood
Bacteria day1
1
1
Bacteria pneumonia
GSM983417
PAXgene whole blood, Bacteria pneumonia,Day_2,ID=1
female
PAXgene whole blood
Bacteria day2
2
1
Bacteria pneumonia
GSM983418
PAXgene whole blood, SIRS,Day_1,ID=4
male
PAXgene whole blood
SIRS day1
1
4
systemic inflammatory response
GSM983419
PAXgene whole blood, Bacteria pneumonia,Day_5,ID=3
male
PAXgene whole blood
Bacteria day5
5
3
Bacteria pneumonia
GSM983420
PAXgene whole blood, Bacteria pneumonia,Day_4,ID=3
male
PAXgene whole blood
Bacteria day4
4
3
Bacteria pneumonia
GSM983421
PAXgene whole blood, Bacteria pneumonia,Day_3,ID=3
male
PAXgene whole blood
Bacteria day3
3
3
Bacteria pneumonia
GSM983422
PAXgene whole blood, Bacteria pneumonia,Day_2,ID=3
male
PAXgene whole blood
Bacteria day2
2
3
Bacteria pneumonia
GSM983423
PAXgene whole blood, Bacteria pneumonia,Day_1,ID=3
male
PAXgene whole blood
Bacteria day1
1
3
Bacteria pneumonia
GSM983424
PAXgene whole blood, Bacteria pneumonia,Day_5,ID=5
male
PAXgene whole blood
Bacteria day5
5
5
Bacteria pneumonia
GSM983425
PAXgene whole blood, Bacteria pneumonia,Day_4,ID=5
male
PAXgene whole blood
Bacteria day4
4
5
Bacteria pneumonia
GSM983426
PAXgene whole blood, Bacteria pneumonia,Day_3,ID=5
male
PAXgene whole blood
Bacteria day3
3
5
Bacteria pneumonia
GSM983427
PAXgene whole blood, Bacteria pneumonia,Day_2,ID=5
male
PAXgene whole blood
Bacteria day2
2
5
Bacteria pneumonia
GSM983428
PAXgene whole blood, Bacteria pneumonia,Day_1,ID=5
male
PAXgene whole blood
Bacteria day1
1
5
Bacteria pneumonia
GSM983429
PAXgene whole blood, influenza A pneumonia,Day_1,ID=9
male
PAXgene whole blood
Flu day1
1
9
influenza A pneumonia
GSM983430
PAXgene whole blood, influenza A pneumonia,Day_2,ID=9
male
PAXgene whole blood
Flu day2
2
9
influenza A pneumonia
GSM983431
PAXgene whole blood, influenza A pneumonia,Day_3,ID=9
male
PAXgene whole blood
Flu day3
3
9
influenza A pneumonia
GSM983432
PAXgene whole blood, influenza A pneumonia,Day_4,ID=9
male
PAXgene whole blood
Flu day4
4
9
influenza A pneumonia
GSM983433
PAXgene whole blood, influenza A pneumonia,Day_5,ID=9
male
PAXgene whole blood
Flu day5
5
9
influenza A pneumonia
GSM983434
PAXgene whole blood, influenza A pneumonia,Day_1,ID=11
female
PAXgene whole blood
Flu day1
1
11
influenza A pneumonia
GSM983435
PAXgene whole blood, influenza A pneumonia,Day_2,ID=11
female
PAXgene whole blood
Flu day2
2
11
influenza A pneumonia
GSM983436
PAXgene whole blood, influenza A pneumonia,Day_3,ID=11
female
PAXgene whole blood
Flu day3
3
11
influenza A pneumonia
GSM983437
PAXgene whole blood, influenza A pneumonia,Day_4,ID=11
female
PAXgene whole blood
Flu day4
4
11
influenza A pneumonia
GSM983438
PAXgene whole blood, influenza A pneumonia,Day_5,ID=11
female
PAXgene whole blood
Flu day5
5
11
influenza A pneumonia
GSM983439
PAXgene whole blood, Bacteria pneumonia,Day_1,ID=10
female
PAXgene whole blood
Bacteria day1
1
10
Bacteria pneumonia
GSM983440
PAXgene whole blood, Bacteria pneumonia,Day_2,ID=10
female
PAXgene whole blood
Bacteria day2
2
10
Bacteria pneumonia
GSM983441
PAXgene whole blood, influenza A pneumonia,Day_1,ID=6
female
PAXgene whole blood
Flu day1
1
6
influenza A pneumonia
GSM983442
PAXgene whole blood, influenza A pneumonia,Day_2,ID=6
female
PAXgene whole blood
Flu day2
2
6
influenza A pneumonia
GSM983443
PAXgene whole blood, influenza A pneumonia,Day_3,ID=6
female
PAXgene whole blood
Flu day3
3
6
influenza A pneumonia
GSM983444
PAXgene whole blood, influenza A pneumonia,Day_4,ID=6
female
PAXgene whole blood
Flu day4
4
6
influenza A pneumonia
GSM983445
PAXgene whole blood, influenza A pneumonia,Day_1,ID=14
female
PAXgene whole blood
Flu day1
1
14
influenza A pneumonia
GSM983446
PAXgene whole blood, influenza A pneumonia,Day_2,ID=14
female
PAXgene whole blood
Flu day2
2
14
influenza A pneumonia
GSM983447
PAXgene whole blood, influenza A pneumonia,Day_3,ID=14
female
PAXgene whole blood
Flu day3
3
14
influenza A pneumonia
GSM983448
PAXgene whole blood, influenza A pneumonia,Day_4,ID=14
female
PAXgene whole blood
Flu day4
4
14
influenza A pneumonia
GSM983449
PAXgene whole blood, influenza A pneumonia,Day_5,ID=14
female
PAXgene whole blood
Flu day5
5
14
influenza A pneumonia
GSM983450
PAXgene whole blood, Bacteria pneumonia,Day_3,ID=10
female
PAXgene whole blood
Bacteria day3
3
10
Bacteria pneumonia
GSM983451
PAXgene whole blood, Bacteria pneumonia,Day_4,ID=10
female
PAXgene whole blood
Bacteria day4
4
10
Bacteria pneumonia
GSM983452
PAXgene whole blood, SIRS,Day_1,ID=12
male
PAXgene whole blood
SIRS day1
1
12
systemic inflammatory response
GSM983453
PAXgene whole blood, SIRS,Day_2,ID=12
male
PAXgene whole blood
SIRS day2
2
12
systemic inflammatory response
GSM983454
PAXgene whole blood, Bacteria pneumonia,Day_5,ID=10
female
PAXgene whole blood
Bacteria day5
5
10
Bacteria pneumonia
GSM983455
PAXgene whole blood, SIRS,Day_1,ID=2
male
PAXgene whole blood
SIRS day1
1
2
systemic inflammatory response
GSM983456
PAXgene whole blood, Bacteria pneumonia,Day_1,ID=7
male
PAXgene whole blood
Bacteria day1
1
7
Bacteria pneumonia
GSM983457
PAXgene whole blood, Bacteria pneumonia,Day_2,ID=7
male
PAXgene whole blood
Bacteria day2
2
7
Bacteria pneumonia
GSM983458
PAXgene whole blood, Bacteria pneumonia,Day_3,ID=7
male
PAXgene whole blood
Bacteria day3
3
7
Bacteria pneumonia
GSM983459
PAXgene whole blood, healthy control,Day_1,ID=48
female
PAXgene whole blood
Control day1
1
48
healthy control
GSM983460
PAXgene whole blood, healthy control,Day_5,ID=48
female
PAXgene whole blood
Control day5
5
48
healthy control
GSM983461
PAXgene whole blood, healthy control,Day_1,ID=51
female
PAXgene whole blood
Control day1
1
51
healthy control
GSM983462
PAXgene whole blood, healthy control,Day_5,ID=51
female
PAXgene whole blood
Control day5
5
51
healthy control
GSM983463
PAXgene whole blood, healthy control,Day_1,ID=50
male
PAXgene whole blood
Control day1
1
50
healthy control
GSM983464
PAXgene whole blood, healthy control,Day_5,ID=50
male
PAXgene whole blood
Control day5
5
50
healthy control
GSM983465
PAXgene whole blood, healthy control,Day_1,ID=43
male
PAXgene whole blood
Control day1
1
43
healthy control
GSM983466
PAXgene whole blood, healthy control,Day_5,ID=43
male
PAXgene whole blood
Control day5
5
43
healthy control
GSM983467
PAXgene whole blood, healthy control,Day_1,ID=57
female
PAXgene whole blood
Control day1
1
57
healthy control
GSM983468
PAXgene whole blood, healthy control,Day_5,ID=57
female
PAXgene whole blood
Control day5
5
57
healthy control
GSM983469
PAXgene whole blood, healthy control,Day_1,ID=40
female
PAXgene whole blood
Control day1
1
40
healthy control
GSM983470
PAXgene whole blood, healthy control,Day_5,ID=40
female
PAXgene whole blood
Control day5
5
40
healthy control
GSM983471
PAXgene whole blood, healthy control,Day_1,ID=41
female
PAXgene whole blood
Control day1
1
41
healthy control
GSM983472
PAXgene whole blood, healthy control,Day_5,ID=41
female
PAXgene whole blood
Control day5
5
41
healthy control
GSM983473
PAXgene whole blood, healthy control,Day_1,ID=34
female
PAXgene whole blood
Control day1
1
34
healthy control
GSM983474
PAXgene whole blood, healthy control,Day_5,ID=34
female
PAXgene whole blood
Control day5
5
34
healthy control
GSM983475
PAXgene whole blood, healthy control,Day_1,ID=46
male
PAXgene whole blood
Control day1
1
46
healthy control
GSM983476
PAXgene whole blood, healthy control,Day_5,ID=46
male
PAXgene whole blood
Control day5
5
46
healthy control
GSM983477
PAXgene whole blood, healthy control,Day_1,ID=58
female
PAXgene whole blood
Control day1
1
58
healthy control
GSM983478
PAXgene whole blood, healthy control,Day_5,ID=58
female
PAXgene whole blood
Control day5
5
58
healthy control
GSM983479
PAXgene whole blood, healthy control,Day_1,ID=52
female
PAXgene whole blood
Control day1
1
52
healthy control
GSM983480
PAXgene whole blood, healthy control,Day_5,ID=52
female
PAXgene whole blood
Control day5
5
52
healthy control
GSM983481
PAXgene whole blood, healthy control,Day_1,ID=47
female
PAXgene whole blood
Control day1
1
47
healthy control
GSM983482
PAXgene whole blood, healthy control,Day_5,ID=47
female
PAXgene whole blood
Control day5
5
47
healthy control
GSM983483
PAXgene whole blood, healthy control,Day_1,ID=35
male
PAXgene whole blood
Control day1
1
35
healthy control
GSM983484
PAXgene whole blood, healthy control,Day_5,ID=35
male
PAXgene whole blood
Control day5
5
35
healthy control
GSM983485
PAXgene whole blood, healthy control,Day_1,ID=49
male
PAXgene whole blood
Control day1
1
49
healthy control
GSM983486
PAXgene whole blood, healthy control,Day_5,ID=49
male
PAXgene whole blood
Control day5
5
49
healthy control
GSM983487
PAXgene whole blood, healthy control,Day_1,ID=53
female
PAXgene whole blood
Control day1
1
53
healthy control
GSM983488
PAXgene whole blood, healthy control,Day_5,ID=53
female
PAXgene whole blood
Control day5
5
53
healthy control
GSM983489
PAXgene whole blood, healthy control,Day_1,ID=44
female
PAXgene whole blood
Control day1
1
44
healthy control
GSM983490
PAXgene whole blood, healthy control,Day_5,ID=44
female
PAXgene whole blood
Control day5
5
44
healthy control
GSM983491
PAXgene whole blood, healthy control,Day_1,ID=45
female
PAXgene whole blood
Control day1
1
45
healthy control
GSM983492
PAXgene whole blood, healthy control,Day_5,ID=45
female
PAXgene whole blood
Control day5
5
45
healthy control
GSM983493
PAXgene whole blood, healthy control,Day_1,ID=42
male
PAXgene whole blood
Control day1
1
42
healthy control
GSM983494
PAXgene whole blood, healthy control,Day_5,ID=42
male
PAXgene whole blood
Control day5
5
42
healthy control
GSM983495
PAXgene whole blood, Bacteria pneumonia,Day_3,ID=39
male
PAXgene whole blood
Bacteria day3
3
39
Bacteria pneumonia
GSM983496
PAXgene whole blood, influenza A pneumonia,Day_3,ID=36
male
PAXgene whole blood
Flu day3
3
36
influenza A pneumonia
GSM983497
PAXgene whole blood, mixed Bacteria and influenza A pneumonia,Day_1,ID=8
female
PAXgene whole blood
Bacteria and Flu day1
1
8
mixed Bacteria and influenza A pneumonia
GSM983498
PAXgene whole blood, mixed Bacteria and influenza A pneumonia,Day_2,ID=8
female
PAXgene whole blood
Bacteria and Flu day2
2
8
mixed Bacteria and influenza A pneumonia
GSM983499
PAXgene whole blood, mixed Bacteria and influenza A pneumonia,Day_3,ID=8
female
PAXgene whole blood
Bacteria and Flu day3
3
8
mixed Bacteria and influenza A pneumonia
GSM983500
PAXgene whole blood, mixed Bacteria and influenza A pneumonia,Day_4,ID=8
female
PAXgene whole blood
Bacteria and Flu day4
4
8
mixed Bacteria and influenza A pneumonia
GSM983501
PAXgene whole blood, SIRS,Day_1,ID=20
male
PAXgene whole blood
SIRS day1
1
20
systemic inflammatory response
GSM983502
PAXgene whole blood, SIRS,Day_2,ID=20
male
PAXgene whole blood
SIRS day2
2
20
systemic inflammatory response
GSM983503
PAXgene whole blood, SIRS,Day_3,ID=20
male
PAXgene whole blood
SIRS day3
3
20
systemic inflammatory response
GSM983504
PAXgene whole blood, SIRS,Day_4,ID=20
male
PAXgene whole blood
SIRS day4
4
20
systemic inflammatory response
GSM983505
PAXgene whole blood, SIRS,Day_1,ID=19
male
PAXgene whole blood
SIRS day1
1
19
systemic inflammatory response
GSM983506
PAXgene whole blood, SIRS,Day_2,ID=19
male
PAXgene whole blood
SIRS day2
2
19
systemic inflammatory response
GSM983507
PAXgene whole blood, SIRS,Day_3,ID=19
male
PAXgene whole blood
SIRS day3
3
19
systemic inflammatory response
GSM983508
PAXgene whole blood, SIRS,Day_1,ID=18
male
PAXgene whole blood
SIRS day1
1
18
systemic inflammatory response
GSM983509
PAXgene whole blood, SIRS,Day_2,ID=18
male
PAXgene whole blood
SIRS day2
2
18
systemic inflammatory response
GSM983510
PAXgene whole blood, Bacteria pneumonia,Day_1,ID=15
female
PAXgene whole blood
Bacteria day1
1
15
Bacteria pneumonia
GSM983511
PAXgene whole blood, Bacteria pneumonia,Day_2,ID=15
female
PAXgene whole blood
Bacteria day2
2
15
Bacteria pneumonia
GSM983512
PAXgene whole blood, Bacteria pneumonia,Day_3,ID=15
female
PAXgene whole blood
Bacteria day3
3
15
Bacteria pneumonia
GSM983513
PAXgene whole blood, Bacteria pneumonia,Day_4,ID=15
female
PAXgene whole blood
Bacteria day4
4
15
Bacteria pneumonia
GSM983514
PAXgene whole blood, Bacteria pneumonia,Day_1,ID=13
male
PAXgene whole blood
Bacteria day1
1
13
Bacteria pneumonia
GSM983515
PAXgene whole blood, Bacteria pneumonia,Day_1,ID=17
female
PAXgene whole blood
Bacteria day1
1
17
Bacteria pneumonia
GSM983516
PAXgene whole blood, Bacteria pneumonia,Day_2,ID=17
female
PAXgene whole blood
Bacteria day2
2
17
Bacteria pneumonia
GSM983517
PAXgene whole blood, Bacteria pneumonia,Day_4,ID=17
female
PAXgene whole blood
Bacteria day4
4
17
Bacteria pneumonia
GSM983518
PAXgene whole blood, SIRS,Day_1,ID=16
female
PAXgene whole blood
SIRS day1
1
16
systemic inflammatory response
GSM983519
PAXgene whole blood, SIRS,Day_2,ID=16
female
PAXgene whole blood
SIRS day2
2
16
systemic inflammatory response
GSM983520
PAXgene whole blood, influenza A pneumonia,Day_2,ID=56
male
PAXgene whole blood
Flu day2
2
56
influenza A pneumonia
GSM983521
PAXgene whole blood, influenza A pneumonia,Day_3,ID=56
male
PAXgene whole blood
Flu day3
3
56
influenza A pneumonia
GSM983522
PAXgene whole blood, influenza A pneumonia,Day_4,ID=56
male
PAXgene whole blood
Flu day4
4
56
influenza A pneumonia
GSM983523
PAXgene whole blood, influenza A pneumonia,Day_5,ID=56
male
PAXgene whole blood
Flu day5
5
56
influenza A pneumonia
GSM983524
PAXgene whole blood, influenza A pneumonia,Day_1,ID=54
male
PAXgene whole blood
Flu day1
1
54
influenza A pneumonia
GSM983525
PAXgene whole blood, influenza A pneumonia,Day_2,ID=54
male
PAXgene whole blood
Flu day2
2
54
influenza A pneumonia
GSM983526
PAXgene whole blood, influenza A pneumonia,Day_3,ID=54
male
PAXgene whole blood
Flu day3
3
54
influenza A pneumonia
GSM983527
PAXgene whole blood, influenza A pneumonia,Day_4,ID=54
male
PAXgene whole blood
Flu day4
4
54
influenza A pneumonia
GSM983528
PAXgene whole blood, influenza A pneumonia,Day_5,ID=54
male
PAXgene whole blood
Flu day5
5
54
influenza A pneumonia
GSM983529
PAXgene whole blood, influenza A pneumonia,Day_1,ID=55
female
PAXgene whole blood
Flu day1
1
55
influenza A pneumonia
GSM983530
PAXgene whole blood, influenza A pneumonia,Day_2,ID=55
female
PAXgene whole blood
Flu day2
2
55
influenza A pneumonia
GSM983531
PAXgene whole blood, influenza A pneumonia,Day_3,ID=55
female
PAXgene whole blood
Flu day3
3
55
influenza A pneumonia
GSM983532
PAXgene whole blood, influenza A pneumonia,Day_4,ID=55
female
PAXgene whole blood
Flu day4
4
55
influenza A pneumonia
GSM983533
PAXgene whole blood, influenza A pneumonia,Day_5,ID=55
female
PAXgene whole blood
Flu day5
5
55
influenza A pneumonia
GSM983534
PAXgene whole blood, SIRS,Day_1,ID=28
male
PAXgene whole blood
SIRS day1
1
28
systemic inflammatory response
GSM983535
PAXgene whole blood, SIRS,Day_2,ID=28
male
PAXgene whole blood
SIRS day2
2
28
systemic inflammatory response
GSM983536
PAXgene whole blood, SIRS,Day_3,ID=28
male
PAXgene whole blood
SIRS day3
3
28
systemic inflammatory response
GSM983537
PAXgene whole blood, Bacteria pneumonia,Day_2,ID=31
female
PAXgene whole blood
Bacteria day2
2
31
Bacteria pneumonia
GSM983538
PAXgene whole blood, SIRS,Day_5,ID=28
male
PAXgene whole blood
SIRS day5
5
28
systemic inflammatory response
GSM983539
PAXgene whole blood, Bacteria pneumonia,Day_1,ID=25
female
PAXgene whole blood
Bacteria day1
1
25
Bacteria pneumonia
GSM983540
PAXgene whole blood, Bacteria pneumonia,Day_3,ID=31
female
PAXgene whole blood
Bacteria day3
3
31
Bacteria pneumonia
GSM983541
PAXgene whole blood, SIRS,Day_2,ID=26
female
PAXgene whole blood
SIRS day2
2
26
systemic inflammatory response
GSM983542
PAXgene whole blood, SIRS,Day_3,ID=26
female
PAXgene whole blood
SIRS day3
3
26
systemic inflammatory response
GSM983543
PAXgene whole blood, SIRS,Day_4,ID=26
female
PAXgene whole blood
SIRS day4
4
26
systemic inflammatory response
GSM983544
PAXgene whole blood, influenza A pneumonia,Day_1,ID=36
male
PAXgene whole blood
Flu day1
1
36
influenza A pneumonia
GSM983545
PAXgene whole blood, influenza A pneumonia,Day_4,ID=36
male
PAXgene whole blood
Flu day4
4
36
influenza A pneumonia
GSM983546
PAXgene whole blood, influenza A pneumonia,Day_5,ID=36
male
PAXgene whole blood
Flu day5
5
36
influenza A pneumonia
GSM983547
PAXgene whole blood, mixed Bacteria and influenza A pneumonia,Day_1,ID=37
male
PAXgene whole blood
Bacteria and Flu day1
1
37
mixed Bacteria and influenza A pneumonia
GSM983548
PAXgene whole blood, mixed Bacteria and influenza A pneumonia,Day_2,ID=37
male
PAXgene whole blood
Bacteria and Flu day2
2
37
mixed Bacteria and influenza A pneumonia
GSM983549
PAXgene whole blood, mixed Bacteria and influenza A pneumonia,Day_3,ID=37
male
PAXgene whole blood
Bacteria and Flu day3
3
37
mixed Bacteria and influenza A pneumonia
GSM983550
PAXgene whole blood, mixed Bacteria and influenza A pneumonia,Day_5,ID=37
male
PAXgene whole blood
Bacteria and Flu day5
5
37
mixed Bacteria and influenza A pneumonia
GSM983551
PAXgene whole blood, Bacteria pneumonia,Day_1,ID=39
male
PAXgene whole blood
Bacteria day1
1
39
Bacteria pneumonia
GSM983552
PAXgene whole blood, Bacteria pneumonia,Day_2,ID=39
male
PAXgene whole blood
Bacteria day2
2
39
Bacteria pneumonia
GSM983553
PAXgene whole blood, Bacteria pneumonia,Day_4,ID=39
male
PAXgene whole blood
Bacteria day4
4
39
Bacteria pneumonia
GSM983554
PAXgene whole blood, Bacteria pneumonia,Day_5,ID=39
male
PAXgene whole blood
Bacteria day5
5
39
Bacteria pneumonia
GSM983555
PAXgene whole blood, Bacteria pneumonia,Day_1,ID=22
male
PAXgene whole blood
Bacteria day1
1
22
Bacteria pneumonia
GSM983556
PAXgene whole blood, SIRS,Day_4,ID=28
male
PAXgene whole blood
SIRS day4
4
28
systemic inflammatory response
GSM983557
PAXgene whole blood, Bacteria pneumonia,Day_1,ID=31
female
PAXgene whole blood
Bacteria day1
1
31
Bacteria pneumonia
GSM983558
PAXgene whole blood, Bacteria pneumonia,Day_2,ID=25
female
PAXgene whole blood
Bacteria day2
2
25
Bacteria pneumonia
GSM983559
PAXgene whole blood, Bacteria pneumonia,Day_3,ID=25
female
PAXgene whole blood
Bacteria day3
3
25
Bacteria pneumonia
GSM983560
PAXgene whole blood, Bacteria pneumonia,Day_4,ID=25
female
PAXgene whole blood
Bacteria day4
4
25
Bacteria pneumonia
GSM983561
PAXgene whole blood, Bacteria pneumonia,Day_5,ID=25
female
PAXgene whole blood
Bacteria day5
5
25
Bacteria pneumonia
GSM983562
PAXgene whole blood, SIRS,Day_1,ID=24
male
PAXgene whole blood
SIRS day1
1
24
systemic inflammatory response
GSM983563
PAXgene whole blood, SIRS,Day_2,ID=24
male
PAXgene whole blood
SIRS day2
2
24
systemic inflammatory response
GSM983564
PAXgene whole blood, SIRS,Day_3,ID=24
male
PAXgene whole blood
SIRS day3
3
24
systemic inflammatory response
GSM983565
PAXgene whole blood, SIRS,Day_4,ID=24
male
PAXgene whole blood
SIRS day4
4
24
systemic inflammatory response
GSM983566
PAXgene whole blood, Bacteria pneumonia,Day_2,ID=22
male
PAXgene whole blood
Bacteria day2
2
22
Bacteria pneumonia
GSM983567
PAXgene whole blood, Bacteria pneumonia,Day_3,ID=22
male
PAXgene whole blood
Bacteria day3
3
22
Bacteria pneumonia
GSM983568
PAXgene whole blood, Bacteria pneumonia,Day_4,ID=22
male
PAXgene whole blood
Bacteria day4
4
22
Bacteria pneumonia
GSM983569
PAXgene whole blood, Bacteria pneumonia,Day_5,ID=22
male
PAXgene whole blood
Bacteria day5
5
22
Bacteria pneumonia
GSM983570
PAXgene whole blood, SIRS,Day_1,ID=21
female
PAXgene whole blood
SIRS day1
1
21
systemic inflammatory response
GSM983571
PAXgene whole blood, SIRS,Day_2,ID=21
female
PAXgene whole blood
SIRS day2
2
21
systemic inflammatory response
GSM983572
PAXgene whole blood, SIRS,Day_3,ID=21
female
PAXgene whole blood
SIRS day3
3
21
systemic inflammatory response
GSM983573
PAXgene whole blood, SIRS,Day_4,ID=21
female
PAXgene whole blood
SIRS day4
4
21
systemic inflammatory response
GSM983574
PAXgene whole blood, influenza A pneumonia,Day_1,ID=56
male
PAXgene whole blood
Flu day1
1
56
influenza A pneumonia
GSM983575
PAXgene whole blood, mixed Bacteria and influenza A pneumonia,Day_4,ID=37
male
PAXgene whole blood
Bacteria and Flu day4
4
37
mixed Bacteria and influenza A pneumonia
GSM983576
PAXgene whole blood, influenza A pneumonia,Day_2,ID=36
male
PAXgene whole blood
Flu day2
2
36
influenza A pneumonia
GSM983577
PAXgene whole blood, Bacteria pneumonia,Day_1,ID=38
female
PAXgene whole blood
Bacteria day1
1
38
Bacteria pneumonia
GSM983578
PAXgene whole blood, Bacteria pneumonia,Day_1,ID=29
female
PAXgene whole blood
Bacteria day1
1
29
Bacteria pneumonia
GSM983579
PAXgene whole blood, Bacteria pneumonia,Day_2,ID=29
female
PAXgene whole blood
Bacteria day2
2
29
Bacteria pneumonia
GSM983580
PAXgene whole blood, Bacteria pneumonia,Day_3,ID=29
female
PAXgene whole blood
Bacteria day3
3
29
Bacteria pneumonia
GSM983581
PAXgene whole blood, Bacteria pneumonia,Day_4,ID=29
female
PAXgene whole blood
Bacteria day4
4
29
Bacteria pneumonia
GSM983582
PAXgene whole blood, Bacteria pneumonia,Day_5,ID=29
female
PAXgene whole blood
Bacteria day5
5
29
Bacteria pneumonia
GSM983583
PAXgene whole blood, SIRS,Day_1,ID=27
male
PAXgene whole blood
SIRS day1
1
27
systemic inflammatory response
GSM983584
PAXgene whole blood, SIRS,Day_2,ID=27
male
PAXgene whole blood
SIRS day2
2
27
systemic inflammatory response
GSM983585
PAXgene whole blood, mixed Bacteria and influenza A pneumonia,Day_1,ID=30
female
PAXgene whole blood
Bacteria and Flu day1
1
30
mixed Bacteria and influenza A pneumonia
GSM983586
PAXgene whole blood, mixed Bacteria and influenza A pneumonia,Day_2,ID=30
female
PAXgene whole blood
Bacteria and Flu day2
2
30
mixed Bacteria and influenza A pneumonia
GSM983587
PAXgene whole blood, mixed Bacteria and influenza A pneumonia,Day_3,ID=30
female
PAXgene whole blood
Bacteria and Flu day3
3
30
mixed Bacteria and influenza A pneumonia
GSM983588
PAXgene whole blood, mixed Bacteria and influenza A pneumonia,Day_4,ID=30
female
PAXgene whole blood
Bacteria and Flu day4
4
30
mixed Bacteria and influenza A pneumonia
GSM983589
PAXgene whole blood, mixed Bacteria and influenza A pneumonia,Day_5,ID=30
female
PAXgene whole blood
Bacteria and Flu day5
5
30
mixed Bacteria and influenza A pneumonia
GSM983590
PAXgene whole blood, Bacteria pneumonia,Day_1,ID=32
female
PAXgene whole blood
Bacteria day1
1
32
Bacteria pneumonia
GSM983591
PAXgene whole blood, Bacteria pneumonia,Day_2,ID=32
female
PAXgene whole blood
Bacteria day2
2
32
Bacteria pneumonia
GSM983592
PAXgene whole blood, Bacteria pneumonia,Day_3,ID=32
female
PAXgene whole blood
Bacteria day3
3
32
Bacteria pneumonia

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