Sample Set Annotation Tool: Peripheral blood cells expression data form 7 patients with severe pdm(H1N1) influensa and 7 gender and age matched healthy controls. GSE27131

Study Design
Assay
Sample Info
Files
Info
Samples
Group Sets
Analysis

Purpose

Using PAXgene tubes, peripheral blood samples were collected from seven patients >18 years with documented pdm(H1N1) influenza, bilateral chest infiltrates, and in need of ventilation support. Significant co-morbidity was exclusion criterion. Expression profiles were compared with 7 age matched controls. Using a false discovery rate < 5% and an absolute fold change > 2, 370 genes were differentially expressed in case and controls.A second sample was collected after ca 6 days in the 7 patients and temporal changes in expression profiles investigated. Over expressed putative mediators of inflammatory lung dammage were measured on the protein level.

Hypothesis

Experimental Design

14 patient samples (7 paired samples) and 7 control samples were performed.

Experimental Variables

Controls

Methods

Additional Information

Expected Samples:

21 Samples Loaded: 21

Species

Human (Homo sapiens)

Sample Source

Whole Blood

Disease

H1N1

Treatment Protocol

Growth Protocol

Extraction Protocol

Storage Conditions

Sample Set Spreadsheet

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Samples Preview

Sample ID	!Sample Title	Age	Gender	tissue	group
GSM670449	blood_day0_patient1	54	male	blood	day 0
GSM670450	blood_day6_patient1	54	male	blood	day 6
GSM670451	blood_day0_patient2	38	male	blood	day 0
GSM670452	blood_day6_patient2	38	male	blood	day 6
GSM670453	blood_day0_patient3	59	male	blood	day 0

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File
sampleset4000029_sampleannotations_Group.csv Sample Set Spreadsheet
sampleset4000029_sampleannotations_Group.csv Sample Set Spreadsheet

Samples Viewer / Editor

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Sample ID	!Sample Title	Age	Gender	Tissue	Group	Patient	Control
GSM670449	blood_day0_patient1	54	male	blood	day 0	1
GSM670450	blood_day6_patient1	54	male	blood	day 6	1
GSM670451	blood_day0_patient2	38	male	blood	day 0	2
GSM670452	blood_day6_patient2	38	male	blood	day 6	2
GSM670453	blood_day0_patient3	59	male	blood	day 0	3
GSM670454	blood_day6_patient3	59	male	blood	day 6	3
GSM670455	blood_day0_patient4	28	female	blood	day 0	4
GSM670456	blood_day6_patient4	28	female	blood	day 6	4
GSM670457	blood_day0_patient5	38	male	blood	day 0	5
GSM670458	blood_day6_patient5	38	male	blood	day 6	5
GSM670459	blood_day0_patient6	46	male	blood	day 0	6
GSM670460	blood_day6_patient6	46	male	blood	day 6	6
GSM670461	blood_day0_patient7	25	male	blood	day 0	7
GSM670462	blood_day6_patient7	25	male	blood	day 6	7
GSM670463	Blood_Control 1	41	male	blood	Control		1
GSM670464	Blood_Control 2	48	male	blood	Control		2
GSM670465	Blood_Control 3	38	female	blood	Control		3
GSM670466	Blood_Control 4	26	male	blood	Control		4
GSM670467	Blood_Control 5	41	male	blood	Control		5
GSM670468	Blood_Control 6	40	female	blood	Control		6
GSM670469	Blood_Control 7	35	female	blood	Control		7

Group Sets View in Gene Expression Browser

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Module Analysis

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